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The Journal: plain-language pieces translating real psychedelic science. What the research actually says, who's doing it, and why we fund it. No hype, no noise.

Latest field notes

Evidence-led, plainly written, every source cited
Overhead still life: a crushed cigarette packet and two stubbed-out cigarettes on the left, three dried psilocybe mushrooms in a row on the rightResearch Watch

A single dose beat nicotine patches, and the caveats matter

At six months, 40.5% of the psilocybin group were verified as still not smoking, against 10.0% on patches. Both groups also had 13 weeks of therapy,...

By Stem & Cap

A single dried psilocybe mushroom on a bone-white surface, lit hard from one side casting a long shadowResearch Watch

What “remission” actually meant in the psilocybin depression trials

The largest trial of its kind gave 233 people with treatment-resistant depression a single dose. The three-week result was real. The definition of remission was narrower...

By Stem & Cap

A seated figure in outline whose upper edge dissolves into a field of fine dots and small starsMind & Mood

Ego dissolution, and why it isn't scary on paper

The most mythologised part of the experience, described in the careful language researchers actually use, including what they measure and what they still can't claim.

By Stem & Cap

Two identical plain capsules side by side, framed by faint patent-medicine sunburst flourishesResearch Watch

Microdosing: the evidence, minus the hype

The best-controlled studies keep finding the same thing, and it isn't what the internet says. Placebo is doing more work here than most people want to...

By Stem & Cap

Ten engraved seeds in a row, the last one germinated into a mushroom with a fine root system belowThe Cause

Where the 10% actually goes

Our pledge in full: what 10% of a sale is, how we choose who receives it, and how to check a research charity before anyone gives...

By Stem & Cap

A neuron drawn as a botanical specimen with new buds sprouting at its branch tips, beside a fainter sparser version of itselfThe Science

Neuroplasticity, the most over-used word in the field

Everyone says psychedelics rewire the brain. Here is what that means at the level of a single synapse, what has only been shown in mice, and...

By Stem & Cap

An engraved drawing of a calm, empty session room: an armchair with a blanket and headphones, a lamp, and two chairs facing itMind & Mood

Set and setting isn't woo, it's protocol

Two words that sound like counterculture shorthand describe the most rigorous part of a clinical psychedelic session: preparation, the room, trained guides, and the weeks afterwards.

By Stem & Cap

An engraved apothecary balance scale weighing three mushrooms against a stack of paper, tipping slightly toward the mushroomsResearch Watch

Phase 3, finally: what the readouts actually say

Psilocybin therapy has cleared its first phase 3 hurdles. The effect is real, smaller than phase 2 suggested, and none of it is peer-reviewed yet.

By Stem & Cap

An anatomical cross-section of a head, the brain drawn as a dense tangle of looping threads with a few coming looseThe Science

The default mode network, in plain English

The brain circuit that narrates your life, why an overactive one tracks with rumination, and what the imaging actually shows under psilocybin.

By Stem & Cap

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